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ProductsBack/YM201636 hydrochloride [371942-69-7]

YM201636 hydrochloride [371942-69-7]

Research Use Only
SYN-1094
SYNkinase
CAS Number371942-69-7
Product group Chemicals
Estimated Purity>95%
Molecular Weight467.4 . 36.5
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Overview

  • Supplier
    SYNkinase
  • Product Name
    YM201636 hydrochloride [371942-69-7]
  • Delivery Days Customer
    10
  • CAS Number
    371942-69-7
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C25H21N7O3 . HCl
  • Molecular Weight
    467.4 . 36.5
  • Scientific Description
    Chemical. CAS: 371942-69-7 (free base). Formula: C25H21N7O3 . HCl. MW: 467.4 . 36.5. YM-201636 is a cell-permeable and selective inhibitor of PIKfyve (IC(50) of 33nM). It disrupts retroviral budding from cells, apparently by interfering with the endosomal sorting complex required for transport (ESCRT) machinery. In adipocytes, YM-201636 also inhibits basal and insulin-activated 2-deoxyglucose uptake (IC(50) of 54nM). - YM-201636 is a cell-permeable and selective inhibitor of PIKfyve (IC(50) of 33nM). It disrupts retroviral budding from cells, apparently by interfering with the endosomal sorting complex required for transport (ESCRT) machinery. In adipocytes, YM-201636 also inhibits basal and insulin-activated 2-deoxyglucose uptake (IC(50) of 54nM).
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    51202000