YM928 [190842-36-5]
HY-118814
CAS Number190842-36-5
Product group Chemicals
Molecular Weight303.77
Overview
- SupplierMedChem Express
- Product NameYM928 [190842-36-5]
- Delivery Days Customer9
- CAS Number190842-36-5
- CertificationResearch Use Only
- Molecular FormulaC14H10ClN3OS
- Molecular Weight303.77
- Scientific DescriptionYM928 is an orally active and noncompetitive alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist. YM928 inhibits AMPA receptor-mediated toxicity in primary rat hippocampal cultures with an IC50 value of 2 microM. YM928 blocks AMPA-induced intracellular calcium influx with an IC50 value of 3 microM and antagonizes AMPA-induced inward currents with an IC50 value of 1 microM. YM928 is promising for research of neurological disorders[1].
- SMILESO=C1N=C(SC2=NC=CC=C12)N(C)C3=CC=C(C=C3)Cl
- UNSPSC12352200