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YNT-185 dihydrochloride [1804978-82-2]

YNT-185 dihydrochloride [1804978-82-2]

T37112
TargetMol Chemicals
CAS Number1804978-82-2
Product group Chemicals
Molecular Weight688.67
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    YNT-185 dihydrochloride [1804978-82-2]
  • Delivery Days Customer
    14
  • CAS Number
    1804978-82-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    YNT-185 dihydrochloride
  • Molecular Formula
    C33H39Cl2N5O5S
  • Molecular Weight
    688.67
  • Scientific Description
    Potent and selective orexin OX2 receptor agonist (EC50 = 28 nM at human OX2 expressed in CHO cells). Displays approximately 100-fold selectivity for OX2 over OX1 (EC50 = 2.75 microM at human OX1 expressed in CHO cells). Depolarizes OX2-expressing histaminergic neurons in mouse brain slices. Increases wake time in wild type mice. Suppresses cataplexy-like symptoms in OX knockout mice.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cl.COc1ccc(cc1S(=O)(=O)Nc1cccc(NCCNC(=O)c2ccccc2N(C)C)c1)-c1cccc(c1)C(=O)N(C)C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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