YS-49 monohydrate

Biorbyt

YS-49 monohydrate

10

Research Use Only

98.00%

C20H22BrNO3

404.3

YS-49 (monohydrate) is an isoquinoline compound alkaloid that functions as a PI3K/Akt activator, specifically targeting a downstream effect of RhoA, to mitigate the activation of RhoA/PTEN in 3-methylcholanthrene-treated cells. It also prevents the angiotensin II (Ang II)-induced proliferation of vascular smooth muscle cells (VSMCs) by promoting the expression of heme oxygenase (HO)-1. Additionally, YS-49 exerts a significant positive inotropic effect by stimulating cardiac beta-adrenoceptors, showcasing its multifaceted pharmacological activities [1] [2] [3].

-20°C

12352200