YTHDC2 antibody [HL1861]

GeneTex

YTHDC2 antibody [HL1861]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

HL1861

1 mg/ml

Unconjugated

YTHDC2

YTH domain containing 2

3'-5' RNA helicase YTHDC2; CAHL; CsA-associated helicase-like protein; hYTHDC2; probable ATP-dependent RNA helicase YTHDC2

Rabbit

IgG

3'-5' RNA helicase YTHDC2

This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3 UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203