
Western Blot Positive WB detected in: Jurkat whole cell lysate, HepG2 whole cell lysate, HL60 whole cell lysate, Rat brain tissue, Rat kidney tissue, Mouse kidney tissue All lanes: YWHAB antibody at 4microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 29, 28 kDa Observed band size: 29 kDa
YWHAB Antibody
CSB-PA01544A0RB
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetYWHAB
Overview
- SupplierCusabio
- Product NameYWHAB Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7529
- Target nameYWHAB
- Target descriptiontyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
- Target synonyms14-3-3 alpha; 14-3-3 protein beta/alpha; epididymis secretory protein Li 1; GW128; HEL-S-1; HS1; KCIP-1; protein 1054; protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; YWHAA
- HostRabbit
- IsotypeIgG
- Scientific DescriptionMembers of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203