YX-2-107 [2417408-46-7]
HY-148530
CAS Number2417408-46-7
Product group Chemicals
Estimated Purity99.22
Molecular Weight889.95
Overview
- SupplierMedChem Express
- Product NameYX-2-107 [2417408-46-7]
- Delivery Days Customer10
- CAS Number2417408-46-7
- CertificationResearch Use Only
- Estimated Purity99.22
- Molecular FormulaC45H51N11O9
- Molecular Weight889.95
- Scientific DescriptionYX-2-107 is a PROTAC (IC50= 4.4 nM) that selectively degrades CDK6. YX-2-107 effectively inhibits RB phosphorylation and FOXM1 expression in vitro and inhibits the development of Ph+ ALL in rats. YX-2-107 can be used in the study of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL)[1].
- SMILESO=C1NC(C(CC1)N2C(C3=C(C2=O)C(OCC(NCCCCNCC(N4CCN(CC4)C5=CN=C(NC6=NC(N(C7CCCC7)C(C(C(C)=O)=C8C)=O)=C8C=N6)C=C5)=O)=O)=CC=C3)=O)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12131703