Bio-Connect

YX-2-107 [2417408-46-7]

HY-148530
MedChem Express
CAS Number2417408-46-7
Product group Chemicals
Estimated Purity99.22
Molecular Weight889.95
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Overview

  • Supplier
    MedChem Express
  • Product Name
    YX-2-107 [2417408-46-7]
  • Delivery Days Customer
    10
  • CAS Number
    2417408-46-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.22
  • Molecular Formula
    C45H51N11O9
  • Molecular Weight
    889.95
  • Scientific Description
    YX-2-107 is a PROTAC (IC50= 4.4 nM) that selectively degrades CDK6. YX-2-107 effectively inhibits RB phosphorylation and FOXM1 expression in vitro and inhibits the development of Ph+ ALL in rats. YX-2-107 can be used in the study of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL)[1].
  • SMILES
    O=C1NC(C(CC1)N2C(C3=C(C2=O)C(OCC(NCCCCNCC(N4CCN(CC4)C5=CN=C(NC6=NC(N(C7CCCC7)C(C(C(C)=O)=C8C)=O)=C8C=N6)C=C5)=O)=O)=CC=C3)=O)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12131703