(Z)-Guggulsterone

MedChem Express

(Z)-Guggulsterone [39025-23-5]

10

39025-23-5

Research Use Only

99.30

C21H28O2

312.45

(Z)-Guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul , inhibits the growth of human prostate cancer cells by causing apoptosis . (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF-VEGF-R2-Akt signaling axis [1] . (Z)-Guggulsterone is also a potent FXR antagonist . (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection [2] .

C[C@@]1(/C2=C/C)[C@](CC2=O)([H])[C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])CC1.[Z]

-20°C,2°C to 8°C

12352200