(Z)-Semaxinib [194413-58-6]

TargetMol Chemicals

(Z)-Semaxinib [194413-58-6]

4

194413-58-6

Research Use Only

(Z)-Semaxinib

99.94%

C15H14N2O

238.28

(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 microM), 20-fold more selective for VEGFR over PDGFRbeta, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative with potential antineoplastic activity.

3 years

C(=C\1/C=2C(NC1=O)=CC=CC2)\C=3NC(C)=CC3C

-20°C

12352200