Zaldaride maleate [109826-27-9]

MedChem Express

Zaldaride maleate [109826-27-9]

10

109826-27-9

Research Use Only

99.7

C30H32N4O6

544.60

Zaldaride maleate (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin. Zaldaride maleate inhibits CaM (calmodulin)-stimulated cAMP phosphodiesterase activity, with an IC50 of 3.3 nM[1][2]. Zaldaride maleate prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR[3].

O=C(O)/C=C\C(O)=O.CC1(C2=CC=CN2C3=CC=CC=C3CO1)CN4CCC(N5C6=C(C=CC=C6)NC5=O)CC4

2°C to 8°C

12352200