ZD0947 [172649-40-0]

MedChem Express

ZD0947 [172649-40-0]

9

172649-40-0

Research Use Only

C17H13F3N2O

318.29

ZD0947 is an ATP-sensitive potassium channel activator with relatively effective activation of smooth muscle KATP channels (SUR2B/Kir6.1 and SUR2B/Kir6.2). ZD0947 partially antagonizes pancreatic KATP channels (SUR1/Kir6.2) and cardiac KATP channels (SUR2A/Kir6.2). ZD0947 is potentially used to inhibit overactive bladder (OAB)[1].

N#CC1=CC=CC([C@@H]2C=C(NC3=C2C(CCC3)=O)C(F)(F)F)=C1

12352200