ZDLD13 [2762278-95-3]
HY-115908
CAS Number2762278-95-3
Product group Chemicals
Molecular Weight302.33
Overview
- SupplierMedChem Express
- Product NameZDLD13 [2762278-95-3]
- Delivery Days Customer10
- CAS Number2762278-95-3
- CertificationResearch Use Only
- Molecular FormulaC18H14N4O
- Molecular Weight302.33
- Scientific DescriptionZDLD13, a beta-carboline, is an orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 0.38 microM. ZDLD13 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD13 shows significant tumor growth inhibition in HCT116 tumor xenograft model[1].
- SMILESO=C(C1=NC=CC2=C1NC3=C2C=CC=C3)NCC4=NC=CC=C4
- UNSPSC12352200