Zetomipzomib (maleate)

MedChem Express

Zetomipzomib (maleate) [2170983-62-5]

5

2170983-62-5

Research Use Only

99.84

C34H46N4O12

702.75

Zetomipzomib (KZR-616) maleate, a first-in-class immunoproteasome inhibitor, selectively targets the LMP7 ( IC 50 : 39/57 nM=hLMP7/mLMP7) and LMP2 ( IC 50 : 131/179 nM=hLMP2/mLMP2) subunits of the immunoproteasome. Zetomipzomib maleate has the potential for the research of multiple autoimmune diseases [1] [2] .

O=C(N[C@@H](CC1=CCCC1)C([C@]2(C)OC2)=O)[C@@H](NC([C@@H](NC(CN3CCOCC3)=O)C)=O)[C@H](O)C4=CC=C(OC)C=C4.O=C(O)/C=C\C(O)=O

2°C to 8°C

12352200