Zibotentan

MedChem Express

Zibotentan [186497-07-4]

5

186497-07-4

99.66

C19H16N6O4S

424.43

Zibotentan (ZD4054) is a potent, selective and orally active endothelin A (ET A ) receptor antagonist with a K i of 13 nM. Zibotentan has no inhibitory effect on ETB. Zibotentan has anticancer effects and can be used for castration-resistant prostate cancer (CRPC) research [1] [2] .

O=S(NC1=NC=C(C)N=C1OC)(C2=CC=CN=C2C3=CC=C(C4=NN=CO4)C=C3)=O

-20°C,2°C to 8°C

12352200