Zimlovisertib [1817626-54-2]

MedChem Express

Zimlovisertib [1817626-54-2]

10

1817626-54-2

CHEMICAL,general_chemicals_reagents

Research Use Only

99.94

C18H20FN3O4

361.37

Zimlovisertib (PF-06650833) is a potent, selective and orally active inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with IC50s of 0.2 and 2.4 nM in the cell and PBMC assay, respectively. Zimlovisertib is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas[1][2].

NC(C1=C(OC)C=C2C(C=CN=C2OC[C@@H]3[C@H](CC)[C@H](F)C(N3)=O)=C1)=O

-20°C, 3 years; 4°C, 2 years (Powder)

12352005