Zimlovisertib

MedChem Express

Zimlovisertib [1817626-54-2]

5

1817626-54-2

Research Use Only

99.94

C18H20FN3O4

361.37

Zimlovisertib (PF-06650833) is a potent, selective and orally active inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with IC 50 s of 0.2 and 2.4 nM in the cell and PBMC assay, respectively. Zimlovisertib is used to treat diseases such as rheumatoid arthritis, lupus, and lymphomas [1] [2] .

NC(C1=C(OC)C=C2C(C=CN=C2OC[C@@H]3[C@H](CC)[C@H](F)C(N3)=O)=C1)=O

-20°C,2°C to 8°C

12352200