Zipalertinib [1661854-97-2]

MedChem Express

Zipalertinib [1661854-97-2]

10

1661854-97-2

Research Use Only

99.62

C23H20N6O

396.44

Zipalertinib (TAS6417; CLN-081) is a highly effective, orally active and pan-mutation-selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP-binding site of the EGFR hinge region, with IC50 values ranging from 1.1-8.0 nM[1][2].

NC1=C2C(N3C(C(C)=C[C@@H](C3)NC(C=C)=O)=C2C4=CC5=CC=CC=C5N=C4)=NC=N1

2°C to 8°C

12352200