ZLD10A [1782064-91-8]
HY-117540
CAS Number1782064-91-8
Product group Chemicals
Molecular Weight612.80
Overview
- SupplierMedChem Express
- Product NameZLD10A [1782064-91-8]
- Delivery Days Customer9
- CAS Number1782064-91-8
- CertificationResearch Use Only
- Molecular FormulaC37H48N4O4
- Molecular Weight612.80
- Scientific DescriptionZLD10A is a highly potent and selective EZH2 inhibitor with the activity of inhibiting H3K27 methylation. ZLD10A can inhibit wild-type and mutant EZH2 with nanomolar potency and has more than 1000-fold selectivity for the other 10 histone methyltransferases. ZLD10A inhibited cell proliferation of DLBCL cell lines in a concentration- and time-dependent manner, showing a potential antiproliferative effect. ZLD10A can be used in the study of EZH2 mutant lymphomas[1].
- SMILESO=C(C1=CC(C2=CC=C(CN3CCOCC3)C=C2)=CC(N(C4CCOCC4)CC)=C1C)NCC5=C(CCCC6)C6=C(C)NC5=O
- UNSPSC12352200