ZLHQ-5f

MedChem Express

ZLHQ-5f [2851977-85-8]

10

Research Use Only

C28H25N5O2

463.53

ZLHQ-5f is a dual CDK2 and Topo I inhibitor with an IC50 of 0.145 microM against CDK2/CycA2. ZLHQ-5f arrests the cell cycle in S-phase, triggers apoptosis in HCT116 cells, and has a good safety profile[1].

N[C@H]1CCN(C1)C2=C3OC4=C(C3=NC5=CC=C(C=C52)C6=CC(NC(C7CC7)=O)=NC=C6)C=CC=C4

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