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ZLMT-12

HY-151436
MedChem Express
Molecular Weight479.02
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ZLMT-12 [2841473-39-8]
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C26H31ClN6O
  • Molecular Weight
    479.02
  • Scientific Description
    ZLMT-12 (compound 35), tacrine derivatives, is a potent, orally active CDK2/9 inhibitor with IC50 values of 0.002 and 0.011 microM for CDK9 and CDK2, respectively. ZLMT-12 has a weak inhibitory effect on AChE (IC50=19.023 microM) and BChE (IC50=2.768 microM). ZLMT-12 has low toxicity and antiproliferative activity. ZLMT-12 induces apoptosis and arrests the cell cycle in the S phase and G2/M phase[1].
  • SMILES
    O=C(C1CC1)NC2=NC=CC(C3=CC=C4N=C5C(CCCCC5)=C(N6C[C@@H](N)CC6)C4=C3)=N2.[H]Cl
  • UNSPSC
    12131703