ZLMT-12
HY-151436
Overview
- SupplierMedChem Express
- Product NameZLMT-12 [2841473-39-8]
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC26H31ClN6O
- Molecular Weight479.02
- Scientific DescriptionZLMT-12 (compound 35), tacrine derivatives, is a potent, orally active CDK2/9 inhibitor with IC50 values of 0.002 and 0.011 microM for CDK9 and CDK2, respectively. ZLMT-12 has a weak inhibitory effect on AChE (IC50=19.023 microM) and BChE (IC50=2.768 microM). ZLMT-12 has low toxicity and antiproliferative activity. ZLMT-12 induces apoptosis and arrests the cell cycle in the S phase and G2/M phase[1].
- SMILESO=C(C1CC1)NC2=NC=CC(C3=CC=C4N=C5C(CCCCC5)=C(N6C[C@@H](N)CC6)C4=C3)=N2.[H]Cl
- UNSPSC12131703