ZM 253270 [169340-04-9]

MedChem Express

ZM 253270 [169340-04-9]

9

169340-04-9

Research Use Only

C22H26ClN7O3

471.94

ZM 253270 is a species-selective non-peptide NK-2 receptor (NK-2R) antagonist. ZM 253270 competitively inhibits the binding of [3H]NKA to native or cloned NK-2R from hamster bladder (Ki=2 nM), but has a weaker inhibitory effect (48-fold) on the binding of [3H]NKA to cloned human NK-2R[1].

O=C(N1CCN(CC1)C2=NC(C(N(C(C)C)C3)=O)=C3C(NC4=CC=C(C=C4)Cl)=N2)/C(C)=N/O

12352200