ZMF-10 [2415295-37-1]

MedChem Express

ZMF-10 [2415295-37-1]

10

2415295-37-1

Research Use Only

C19H17F6N7O

473.37

ZMF-10 is a highly potent PAK1 inhibitor, with IC50s of 174 nM, 1.038 microM and 1.372 microM for PAK1, PAK2 and PAK3, respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis, ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer[1].

O=C(NC1CCN(CC1)C2=C3C=NNC3=NC=N2)NC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4

12131703