ZNF395 Antibody

Cusabio

ZNF395 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

ZNF395

zinc finger protein 395

HD gene regulatory region-binding protein 2; HDBP2; HDBP-2; HD-regulating factor 2; HDRF-2; huntington disease gene regulatory region-binding protein 2; Huntington's disease gene regulatory region-binding protein 2; papillomavirus regulatory factor 1; papillomavirus regulatory factor PRF-1; papillomavirus-binding factor; PBF; PRF1; PRF-1; Si-1-8-14; zinc finger protein 395

Rabbit

IgG

Zinc finger protein 395

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3-CCGG-5 sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntingtons disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.

-20°C or -80°C

12352203