ZNF598 antibody [N1N3]
GTX119245
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetZNF598
Overview
- SupplierGeneTex
- Product NameZNF598 antibody [N1N3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.29 mg/ml
- ConjugateUnconjugated
- Gene ID90850
- Target nameZNF598
- Target descriptionzinc finger protein 598, E3 ubiquitin ligase
- Target synonymsHEL2, E3 ubiquitin-protein ligase ZNF598
- HostRabbit
- IsotypeIgG
- Protein IDQ86UK7
- Protein NameE3 ubiquitin-protein ligase ZNF598
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- De S, Mühlemann O. A comprehensive coverage insurance for cells: revealing links between ribosome collisions, stress responses and mRNA surveillance. RNA Biol. 2022,19(1):609-621. doi: 10.1080/15476286.2022.2065116Read this paper
- Rimal S, Li Y, Vartak R, et al. Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease. Acta Neuropathol Commun. 2021,9(1):169. doi: 10.1186/s40478-021-01268-6Read this paper
- Wan L, Juszkiewicz S, Blears D, et al. Translation stress and collided ribosomes are co-activators of cGAS. Mol Cell. 2021,81(13):2808-2822.e10. doi: 10.1016/j.molcel.2021.05.018Read this paper
- Shin EM, Huynh VT, Neja SA, et al. GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer. Sci Adv. 2021,7(12). doi: 10.1126/sciadv.abe2470Read this paper
- Hildebrandt A, Brüggemann M, Rücklé C, et al. The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Genome Biol. 2019,20(1):216. doi: 10.1186/s13059-019-1814-0Read this paper
- Wang G, Kouwaki T, Okamoto M, et al. Attenuation of the Innate Immune Response against Viral Infection Due to ZNF598-Promoted Binding of FAT10 to RIG-I. Cell Rep. 2019,28(8):1961-1970.e4. doi: 10.1016/j.celrep.2019.07.081Read this paper
- Garzia A, Jafarnejad SM, Meyer C, et al. The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs. Nat Commun. 2017,8:16056. doi: 10.1038/ncomms16056Read this paper
- Juszkiewicz S, Hegde RS. Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination. Mol Cell. 2017,65(4):743-750.e4. doi: 10.1016/j.molcel.2016.11.039Read this paper




