Bio-Connect

ZNF598 antibody [N1N3]

GTX119245
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetZNF598
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Overview

  • Supplier
    GeneTex
  • Product Name
    ZNF598 antibody [N1N3]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Knockdown/Knockout validation was supported by references (PMID:28065601)
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.29 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID90850
  • Target name
    ZNF598
  • Target description
    zinc finger protein 598, E3 ubiquitin ligase
  • Target synonyms
    E3 ubiquitin-protein ligase ZNF598; HEL2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ86UK7
  • Protein Name
    E3 ubiquitin-protein ligase ZNF598
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A comprehensive coverage insurance for cells: revealing links between ribosome collisions, stress responses and mRNA surveillance. De S et al., 2022, RNA Biol
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  • Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimers disease. Rimal S et al., 2021 Oct 18, Acta Neuropathol Commun
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  • Translation stress and collided ribosomes are co-activators of cGAS. Wan L et al., 2021 Jul 1, Mol Cell
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  • GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERalpha glycosylation and stability to cancer. Shin EM et al., 2021 Mar, Sci Adv
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  • The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Hildebrandt A et al., 2019 Oct 22, Genome Biol
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  • Attenuation of the Innate Immune Response against Viral Infection Due to ZNF598-Promoted Binding of FAT10 to RIG-I. Wang G et al., 2019 Aug 20, Cell Rep
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  • The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs. Garzia A et al., 2017 Jul 7, Nat Commun
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  • Initiation of Quality Control during Poly(A) Translation Requires Site-Specific Ribosome Ubiquitination. Juszkiewicz S et al., 2017 Feb 16, Mol Cell
    Read more