ZNL0325

MedChem Express

ZNL0325

14

Research Use Only

C15H20N6O2

316.36

ZNL0325 is a covalent probe based on pyrazolopyrimidine. ZNL0325 features an acrylamide side chain at the C3 position, which is capable of forming covalent bonds with multiple kinases that possess a cysteine at the alphaD-1 position, including BTK, EGFR, BLK, and JAK3. ZNL0325 can be used in the research of creating structurally distinct covalent kinase inhibitors[1].

CC(C)(N1C2=NC=NC(N)=C2C(OC3CN(C3)C(C=C)=O)=N1)C

12352200