ZO-3 antibody

GeneTex

ZO-3 antibody

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

TJP3

tight junction protein 3

tight junction protein 3 (zona occludens 3); tight junction protein ZO-3; ZO3; ZO-3; zona occludens protein 3; zonula occludens protein 3

Rabbit

IgG

Tight junction protein ZO-3

The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012]

-20°C or -80°C,2°C to 8°C

12352203