Bio-Connect

Zofenoprilat [75176-37-3]

HY-133829
MedChem Express
CAS Number75176-37-3
Product group Chemicals
Estimated Purity97.5
Molecular Weight325.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Zofenoprilat [75176-37-3]
  • Delivery Days Customer
    5
  • CAS Number
    75176-37-3
  • Certification
    Research Use Only
  • Estimated Purity
    97.5
  • Hazard Information
    h301, h311, h331
  • Molecular Formula
    C15H19NO3S2
  • Molecular Weight
    325.45
  • Scientific Description
    Zofenoprilat is an orally active inhibitor for angiotensin converting enzyme (ACE) with an IC50 of 1.7 nM. Zofenoprilat inhibits the expression of angiotensin II, reduces the blood pressure, exhibits thus cardioprotective and renalprotective activity. Zofenoprilat promotes the NO production, decreases endothelin-1 (ET-1) expression, exhibits protective effect on vascular endothelial function. Zofenoprilat regulates oxidative stress-related molecules, exhibits antioxidant activity[1][2].
  • SMILES
    SC[C@@H](C)C(N1[C@@H](C[C@@H](C1)SC2=CC=CC=C2)C(O)=O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200