ZW-1226 [2351940-23-1]

TargetMol Chemicals

ZW-1226 [2351940-23-1]

9

Research Use Only

C25H16N4O3

420.42

ZW-1226 is a selective MRP1 inhibitor that reduces the uptake activity of MRP1 vesicles by 65% at a concentration of 5 microM. It inhibits MRP1 in a GSH-dependent manner and exhibits considerable selectivity towards MRP1 over other primary ABC transport proteins (including P-gp, BCRP, MRP2, and MRP3).

N#CC=1C=CC=2C=C3C(=O)NC(=O)N=C3N(C4=CC=C(OCC=5C=CC=CC5)C=C4)C2C1

-20°C

12352200