16-epi Latrunculin B [444911-05-1]

TargetMol Chemicals

16-epi Latrunculin B [444911-05-1]

999

444911-05-1

Chemical

Research Use Only

16-epi Latrunculin B

C20H29NO5S

395.5

16-epiLatrunculin B, a stereoisomer of the actin polymerization inhibitor latrunculin B, was initially isolated from the Red Sea sponge N. magnifica. At concentrations of 5-10 microg/ml, it disrupts microfilament activity in actin disruption assays and exhibits cytotoxic effects on mouse KA31T and NIH3T3 tumor cells, with GI50 values of 1 and 4 microg/ml, respectively. Furthermore, it shows antiviral activity against herpes simplex type 1 virus, with an ED50 of 1 microg/ml.

3 years

-20°C

12352200