17-AAG
ORB1089337
CAS Number75747-14-7
Product group Chemicals
Molecular Weight585.6884
Overview
- SupplierBiorbyt
- Product Name17-AAG [75747-14-7]
- Delivery Days Customer10
- CAS Number75747-14-7
- CertificationResearch Use Only
- Molecular FormulaC31H43N3O8
- Molecular Weight585.6884
- Scientific Description17-AAG (17-N-Allylamino-17-demethoxygeldanamycin), also known by its NSC number 330507 and CP number 127374, is a well-studied inhibitor of Heat Shock Protein 90 (HSP90). HSP90 is a molecular chaperone that plays a critical role in the stabilization and activation of a wide range of client proteins, many of which are involved in oncogenic processes. By inhibiting HSP90, 17-AAG disrupts the function of these client proteins, leading to the degradation of oncogenic proteins and ultimately inhibiting cancer cell growth and survival.
- SMILESO=C(C(NC(/C(C)=C/C=C[C@H](OC)[C@H](/C(C)=C/[C@@H]([C@H]([C@H](C[C@@H](C1)C)OC)O)C)OC(N)=O)=O)=CC2=O)C1=C2NCC=C
- UNSPSC12352200
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