17-trifluoromethylphenyl trinor Prostaglandin F2alpha [221246-34-0]

TargetMol Chemicals

17-trifluoromethylphenyl trinor Prostaglandin F2alpha [221246-34-0]

16

221246-34-0

Research Use Only

17-trifluoromethylphenyl trinor Prostaglandin F2alfa

C24H31F3O5

456.502

17-phenyl trinor prostaglandin F2alpha (17-phenyl trinor PGF2alpha) derivatives have been approved for the treatment of glaucoma, with unsubstituted or meta-substituted aromatic derivatives being the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF2alpha, which contains an aromatic ring reminiscent of the trifluoromethyl-phenoxy ring in travoprost ((+)-fluprostenol isopropyl ester), is expected to act similarly to the free acid form of travoprost as an ocular hypotensive agent. Additionally, 17-phenyl trinor PGF2alpha is a potent luteolytic and abortifacient with a potency equal to or greater than that of fluprostenol and cloprostenol.

3 years

O[C@@H](CCc1cccc(c1)C(F)(F)F)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O

-20°C

12352200