2-Methoxyestradiol

MedChem Express

2-Methoxyestradiol [362-07-2]

10

362-07-2

Research Use Only

99.82

C19H26O3

302.41

2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17beta-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules . 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa [1] [2] [3] [4] [5] [6] .

OC1=CC2=C([C@]3(CC[C@@]4([C@H](CC[C@]4([C@@]3(CC2)[H])[H])O)C)[H])C=C1OC

-20°C,2°C to 8°C

12352200