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2-Methoxyestradiol

M1992
AbMole BioScience
CAS Number362-07-2
Product group Chemicals
Estimated Purity0.9845
Molecular Weight302.41
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    2-Methoxyestradiol
  • Delivery Days Customer
    9
  • CAS Number
    362-07-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9845
  • Molecular Formula
    C19H26O3
  • Molecular Weight
    302.41
  • Scientific Description
    2-methoxyestradiol (2-ME2), an endogenous metabolite of 17bèta -estradiol (E2) with oral activity, is an apoptosis inducer and angiogenesis inhibitor with effective antitumor activity. Methoxyestradiol can also destabilize microtubules. Methoxyestradiol is a potent inhibitor of superoxide dismutase (SOD) and reactive oxygen species (ROS) that can induce autophagy in transformed cell line HEK293, cancer cell line U87 and HeLa.
  • SMILES
    COC1=C(O)C=C2CCC3C(CCC4(C)C(O)CCC34)C2=C1
  • UNSPSC
    12352200

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