3-Hydroxy Midostaurin [179237-49-1]
T12610L
CAS Number179237-49-1
Product group Chemicals
Molecular Weight586.648
Overview
- SupplierTargetMol Chemicals
- Product Name3-Hydroxy Midostaurin [179237-49-1]
- Delivery Days Customer9
- CAS Number179237-49-1
- CertificationResearch Use Only
- Chemical Name3-Hydroxy Midostaurin
- Molecular FormulaC35H30N4O5
- Molecular Weight586.648
- Scientific Description3-Hydroxy Midostaurin (CGP 52421), a PKC412 metabolite, inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50 values of approximately 132 nM in culture medium and 9.8 microM in plasma. Although less selective, it shows greater cytotoxicity compared to PKC412[1].
- Shelf life instruction3 years
- SMILESCO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4C(O)NC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1
- Storage Instruction-20°C
- UNSPSC12352200
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