3MB-PP1 [956025-83-5]
HY-102069
CAS Number956025-83-5
Product group Chemicals
Estimated Purity99.66
Molecular Weight295.38
Overview
- SupplierMedChem Express
- Product Name3MB-PP1 [956025-83-5]
- Delivery Days Customer10
- CAS Number956025-83-5
- CertificationResearch Use Only
- Estimated Purity99.66
- Hazard Informationh302, h315, h319
- Molecular FormulaC17H21N5
- Molecular Weight295.38
- Scientific Description3MB-PP1, a bulky purine analog, is a Polo-like kinase 1 (Plk1) inhibitor. 3MB-PP1 blocks mitotic progression and cell division arise through target Plk1 in in cells expressing analog-sensitive Plk1 alleles. 3MB-PP1 specifically inhibits the activity of analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK; IC50=2 microM). 3MB-PP1 can be used for the research of hypha formation of Candida albicans and cell division[1][2][3].
- SMILESNC1=C2C(N(C(C)(C)C)N=C2CC3=CC=CC(C)=C3)=NC=N1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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