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3MB-PP1

M49490
AbMole BioScience
CAS Number956025-83-5
Product group Chemicals
Molecular Weight295.38
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    3MB-PP1
  • Delivery Days Customer
    9
  • CAS Number
    956025-83-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C17H21N5
  • Molecular Weight
    295.38
  • Scientific Description
    3MB-PP1 is a bulky purine analog and inhibitor of Polo-like kinase 1 (Plk1) that blocks mitotic progression and cytokinesis by targeting Plk1 in cells expressing the analog-sensitive Plk1 allele. 3MB-PP1 also specifically inhibits the activity of Leu93 mutant Zipper-interacting Ssn3 (Cdk8). 3MB-PP1 inhibits the activity of Leu93 mutant Zipper-interacting Ssn3 (Cdk8). In addition, 3MB-PP1 specifically inhibits the activity of analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits the Leu93 mutant Zipper-interacting protein kinase (Leu93-ZIPK; IC50=2 uM). 3MB-PP1 can be used in the mycelium of Candida albicans. 3MB-PP1 can be used in studies related to mycelium formation and cell division in Candida albicans.
  • UNSPSC
    12352200

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