(3S,4S)-PF-06459988 [1858291-14-1]

TargetMol Chemicals

(3S,4S)-PF-06459988 [1858291-14-1]

14

1858291-14-1

Research Use Only

(3S,4S)-PF-06459988

C19H22ClN7O3

431.88

(3S, 4S)-PF-06459988 is the less active S enantiomer of PF-06459988, a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR), exhibiting excellent selectivity against EGFR wild-type due to its minimally reactive electrophile, reducing off-target labeling likelihood.

3 years

CO[C@@H]1CN(C[C@H]1COc1nc(Nc2cnn(C)c2)nc2[nH]cc(Cl)c12)C(=O)C=C

-20°C

12352200