4,5-Dimethoxycanthin-6-one

MedChem Express

4,5-Dimethoxycanthin-6-one [18110-87-7]

5

18110-87-7

Research Use Only

98.68

C16H12N2O3

280.28

4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2 -mediated phenacetin O-deethylation with an IC 50 value of 1.7microM and a K i value of 2.6 microM. 4,5-Dimethoxycanthin-6-one, as an alkaloid, is isolated from the wood of Picrasma quassioides BENNET (Simaroubaceae) [1] [2] .

O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4)C(OC)=C1OC

2°C to 8°C

12352200