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4,5-Dimethoxycanthin-6-one [18110-87-7]

4,5-Dimethoxycanthin-6-one [18110-87-7]

TN3013
TargetMol Chemicals
CAS Number18110-87-7
DownloadMSDS
Product group Chemicals
Estimated Purity98.84%
Molecular Weight280.28
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    4,5-Dimethoxycanthin-6-one [18110-87-7]
  • Delivery Days Customer
    9
  • CAS Number
    18110-87-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    4,5-Dimethoxycanthin-6-one
  • Estimated Purity
    98.84%
  • Molecular Formula
    C16H12N2O3
  • Molecular Weight
    280.28
  • Scientific Description
    4,5-Dimethoxycanthin-6-one is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity against Staphylococcus aureus and its drug-resistant strains. It is a potent, non-competitive inhibitor of CYP1A2-mediated phenacetin O-deethylation (IC50: 1.7 microM, Ki: 2.6 microM) and a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase. Additionally, it exhibits cytotoxicity to tumor cell lines U937 and HepG2.
  • Shelf life instruction
    3 years
  • SMILES
    COc1c(OC)c(=O)n2c3ccccc3c3ccnc1c23
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200