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Chemical Structure
Chemical Structure
Chemical Structure

5-CFDA

CDX-C0039
Chemodex
CAS Number79955-27-4
Product group Chemicals
Estimated Purity>95%
Molecular Weight460.39
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Overview

  • Supplier
    Chemodex
  • Product Name
    5-CFDA [79955-27-4]
  • Delivery Days Customer
    10
  • CAS Number
    79955-27-4
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C25H16O9
  • Molecular Weight
    460.39
  • Scientific Description
    Carboxyfluorescein diacetate (CFDA), which was originally used to measure intracellular pH but was soon adapted for use as a cell viability indicator. Upon hydrolysis by intracellular nonspecific esterases, CFDA forms carboxyfluorescein. As compared with fluorescein, carboxyfluorescein contains extra negative charges and is therefore better retained in cells CFDA is moderately permeant to most cell membranes, with uptake greater at pH 6.2 than at pH 7.41. CFDA has been used as a viability probe with a variety of cells, including bacteria, fungi (e.g. Saccharomyces cerevisiae), spermatozoa, natural killer (NK) cells and tumor cells. - Chemical. CAS: 79955-27-4. Formula: C25H16O9. MW: 460.39. Synthetic. Carboxyfluorescein diacetate (CFDA), which was originally used to measure intracellular pH but was soon adapted for use as a cell viability indicator. Upon hydrolysis by intracellular nonspecific esterases, CFDA forms carboxyfluorescein. As compared with fluorescein, carboxyfluorescein contains extra negative charges and is therefore better retained in cells CFDA is moderately permeant to most cell membranes, with uptake greater at pH 6.2 than at pH 7.41. CFDA has been used as a viability probe with a variety of cells, including bacteria, fungi (e.g. Saccharomyces cerevisiae), spermatozoa, natural killer (NK) cells and tumor cells.
  • SMILES
    CC(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=C1C=CC(=C3)C(O)=O)C1=CC=C(OC(C)=O)C=C1O2
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116134

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Product group Chemicals
TargetMol Chemicals
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Molecular Weight460.39
  • SizePrice