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5-Vinyl-2-deoxyuridine (5-VdU), 5-Ethenyl-2-deoxyuridine [55520-67-7]

Research Use Only
CLK-050-10
Jena Bioscience
CAS Number55520-67-7
Product group Chemicals
Estimated Purity≥98%
Molecular Weight254.24 g/mol
€ 193,00
10 mg
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Overview

  • Supplier
    Jena Bioscience
  • Product Name
    5-Vinyl-2-deoxyuridine (5-VdU), 5-Ethenyl-2-deoxyuridine [55520-67-7]
  • Delivery Days Customer
    5
  • CAS Number
    55520-67-7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Molecular Formula
    C11H14N2O5
  • Molecular Weight
    254.24 g/mol
  • Scientific Description
    5-VdU (5-Vinyl-2-deoxyuridine) can be used as a replacement for BrdU (5-Bromo-2-deoxyuridine) or the copper-catalyst requiring 5-EdU (5-Ethynyl-2-deoxyuridine) to measure de novo DNA synthesis during the S-phase of the cell cycle. 5-VdU is cell permeable and incorporates into replicating DNA instead of its natural analog thymidine. The resulting vinyl-functionalized DNA can subsequently be detected via Cu(I)-free Alkene-Tetrazine Ligation that offers the choice to introduce a Biotin group (via Tetrazines of Biotin) for subsequent purification tasks or a fluorescent group (via Tetrazines of fluorescent dyes) for subsequent microscopic imaging [1].
  • SMILES
    n1(cc(c(=O)[nH]c1=O)C=C)[C@H]1C[C@@H]([C@H](O1)CO)O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200