Bio-Connect

53BP1 antibody

Research Use Only
GTX70316
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetTP53BP1
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    53BP1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    For WB: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID7158
  • Target name
    TP53BP1
  • Target description
    tumor protein p53 binding protein 1
  • Target synonyms
    53BP1; p202; p53-binding protein 1; p53BP1; TDRD30; TP53-binding protein 1; tumor protein 53-binding protein, 1; tumor suppressor p53-binding protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ12888
  • Protein Name
    TP53-binding protein 1
  • Scientific Description
    This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203