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5(S)-HEPE [92008-51-0]

5(S)-HEPE [92008-51-0]

T84567
TargetMol Chemicals
CAS Number92008-51-0
DownloadMSDS
Product group Chemicals
Molecular Weight318.5
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    5(S)-HEPE [92008-51-0]
  • Delivery Days Customer
    16
  • CAS Number
    92008-51-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    5(S)-HEPE
  • Molecular Formula
    C20H30O3
  • Molecular Weight
    318.5
  • Scientific Description
    5(S)-HEPE, an active metabolite of eicosapentaenoic acid (EPA), is produced via the action of 5-lipoxygenase (5-LO). This compound functions as an agonist for G protein-coupled receptor 119 (GPR119), promoting cAMP accumulation in CHO-K1 cells expressing human GPR119 at 10 microM concentration. Additionally, 5(S)-HEPE enhances glucose-stimulated insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells at the same concentration. Notably, serum levels of 5(S)-HEPE are increased in hyperlipidemia patients.
  • Shelf life instruction
    3 years
  • SMILES
    [C@@H](/C=C/C=C\C/C=C\C/C=C\C/C=C\CC)(CCCC(O)=O)O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200