6-Diazo-5-oxo-L-norleucine

Selleck Chemicals

6-Diazo-5-oxo-L-norleucine [157-03-9]

9

Research Use Only

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6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON), an antibiotic isolated from Streptomyces, is a glutaminase antagonist with IC50 of ~1 mM for cKGA (kidney-type glutaminase). 6-Diazo-5-oxo-L-norleucine exhibits analgesic, antibacterial, antiviral and anticancer properties.

51202000