7-[(Benzyloxy)methoxy]-4-(trifluoromethyl)-2H-chromen-2-one [277309-33-8] [277309-33-8]

Chemodex

7-[(Benzyloxy)methoxy]-4-(trifluoromethyl)-2H-chromen-2-one [277309-33-8] [277309-33-8]

10

277309-33-8

Research Use Only

>98%

Warning

C18H13F3O4

350.29

BOMFC is a fluorescent probe used to study the activity of cytochrome P450 (CYP) enzymes, specifically insecticide metabolism and pyrethroid resistance. It serves as a sensitive substrate in fluorescence-based assays to assess the inhibitory action of potential synergists and to understand the interaction of pyrethroids like transfluthrin with CYP enzymes. BOMFC is a caged coumarin fluorophore that stays dark until cleaved by an enzyme. Once deprotected, it lights up blue, a classic turn-on fluorescent probe for enzyme activity. Once the protecting group is removed, the free hydroxycoumarin is formed. This molecule is now strongly fluorescent, Excitation: ~350-380 nm, Emission: ~450-480 nm (bright blue fluorescence). - Chemical. CAS: 277309-33-8. Formula: C18H13F3O4. MW: 350.29. BOMFC is a fluorescent probe used to study the activity of cytochrome P450 (CYP) enzymes, specifically insecticide metabolism and pyrethroid resistance. It serves as a sensitive substrate in fluorescence-based assays to assess the inhibitory action of potential synergists and to understand the interaction of pyrethroids like transfluthrin with CYP enzymes. BOMFC is a caged coumarin fluorophore that stays dark until cleaved by an enzyme. Once deprotected, it lights up blue, a classic turn-on fluorescent probe for enzyme activity. Once the protecting group is removed, the free hydroxycoumarin is formed. This molecule is now strongly fluorescent, Excitation: ~350-380 nm, Emission: ~450-480 nm (bright blue fluorescence).

O=C1OC=2C=C(OCOCC=3C=CC=CC3)C=CC2C(=C1)C(F)(F)F

2°C to 8°C,RT

12162000