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ProductsBack/A 196

A 196

M6362
AbMole BioScience
CAS Number1982372-88-2
Product group Chemicals
Molecular Weight359.25
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    A 196
  • Delivery Days Customer
    9
  • CAS Number
    1982372-88-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C18H16Cl2N4
  • Molecular Weight
    359.25
  • Scientific Description
    A-196 is a potent selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively, and biochemically inhibits SUV4-20 in a substrate-competitive manner. In addition, A-196 is a first-in-class chemical probe for SUV4-20, which can be used to study the role of histone methyltransferases in genome integrity.
  • SMILES
    ClC1=C(Cl)C=C2C(=C1)C(=NN=C2C3=CC=NC=C3)NC4CCCC4
  • UNSPSC
    12352200