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A-769662

A-769662

Research Use Only
27057
BPS Bioscience
CAS Number844499-71-4
Product group Chemicals
Estimated Purity≥99%
Molecular Weight360.4 Da
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    A-769662
  • Delivery Days Customer
    7
  • CAS Number
    844499-71-4
  • Certification
    Research Use Only
  • Estimated Purity
    ≥99%
  • Molecular Formula
    C20H12N2O3S
  • Molecular Weight
    360.4 Da
  • Scientific Description
    A-769662 is a potent, reversible activator of AMP-activated protein kinase (AMPK). AMPK is an alphabetagamma heterotrimer and plays an important role in regulating cellular and whole-body metabolism. A-769662 only activates AMPK heterotrimers containing the beta1 subunit. A-769662 activates AMPK through the beta subunit carbohydrate-binding module and the gamma subunit but not the AMP-binding sites. A-769662 stimulated partially purified rat liver AMPK with an EC50 of 0.8 microM and inhibited fatty acid synthesis in primary rat hepatocytes with an IC50 of 3.2 microM.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200