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AACOCF3 [149301-79-1]

Research Use Only
HY-108611
MedChem Express
CAS Number149301-79-1
Product group Chemicals
Estimated Purity99.0
Molecular Weight356.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AACOCF3 [149301-79-1]
  • Delivery Days Customer
    10
  • CAS Number
    149301-79-1
  • Certification
    Research Use Only
  • Concentration
    28.05 mM
  • Estimated Purity
    99.0
  • Molecular Formula
    C21H31F3O
  • Molecular Weight
    356.47
  • Scientific Description
    AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the research of cardiovascular disease[1][2][3].
  • SMILES
    CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(C(F)(F)F)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200