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AACOCF3 [149301-79-1]

AACOCF3 [149301-79-1]

Research Use Only
T21681
TargetMol Chemicals
CAS Number149301-79-1
DownloadMSDS
Product group Chemicals
Estimated Purity0.99
Molecular Weight356.47
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    AACOCF3 [149301-79-1]
  • Delivery Days Customer
    16
  • CAS Number
    149301-79-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    AACOCF3
  • Estimated Purity
    0.99
  • Molecular Formula
    C21H31F3O
  • Molecular Weight
    356.47
  • Scientific Description
    AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid and a potent, selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). By blocking the production of arachidonate and 12-hydroxyeicosatetraenoic acid in calcium ionophore-challenged platelets, AACOCF3 hinders their synthesis. Additionally, AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets, making it promising for cardiovascular disease research.
  • Shelf life instruction
    3 years
  • SMILES
    C(\CCCC(C(F)(F)F)=O)=C\C/C=C\C/C=C\C/C=C\CCCCC
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200