AAV6 Luciferase-eGFP

BPS Bioscience

AAV6 Luciferase-eGFP

7

Research Use Only

Adeno-Associated Virus serotype 6 (AAV6) appears to be related to AAV1 by sequence analysis and shows the highest transduction efficiency in pancreatic beta-cells compared to other AAV serotypes. These AAV6 particles constitutively express the firefly (Photinus pyralis) luciferase and enhanced Green Fluorescent Protein (eGFP) genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and eGFP as two separate proteins.

-80°C

12352200