ABBV-744

MedChem Express

ABBV-744 [2138861-99-9]

10

2138861-99-9

Research Use Only

99.97

C28H30FN3O4

491.55

ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC 50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with agent-like properties enable the investigation of its antitumor efficacy and tolerability [1] .

CC(O)(C)C1=CC(C(C2=C3NC(C(NCC)=O)=C2)=CN(C)C3=O)=C(OC4=C(C)C=C(F)C=C4C)C=C1

2°C to 8°C

12352200